Elemental Analysis and Cryo-STEM Tomography of Vitrified Cells

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منابع مشابه

Cryo-electron microscopy of vitrified specimens.

Present addresses: ' Centre de Microscopie Electronique (CME), 27 Rue du Bugnon, CH-105 Lausanne; Laboratoire Europeen de Biologie Moleculaire, I.L.L. 156X; F-38042 Grenoble Cedex; ' The Institute of Biophysics, Academica Sinica, Peking, China; 4 Institut de Biochimie, n Rue Humann, F-67000 Strasbourg; 5 Centre de Genetique Moleculaire, C.N.R.S., F-9H90 Gif/Yvette; 6 Howard Hughes Medical Insti...

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Cryo-electron tomography enables three-dimensional insights into the macromolecular architecture of cells in a close-to-life state. However, it is limited to thin specimens, <1.0 μm in thickness, typically restricted to the peripheral areas of intact eukaryotic cells. Analysis of tissue ultrastructure, on the other hand, requires physical sectioning approaches, preferably cryo-sectioning, follo...

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ژورنال

عنوان ژورنال: Microscopy and Microanalysis

سال: 2019

ISSN: 1431-9276,1435-8115

DOI: 10.1017/s1431927619006159